Lactuca capensis reverses memory deficits in Aβ1‐42‐induced an animal model of Alzheimer's disease

We investigated the neuropharmacological effects of the methanolic extract from Lactuca capensis Thunb. leaves (100 and 200 mg/kg) for 21 days on memory impairment in an Alzheimer's disease (AD) rat model produced by direct intraventricular delivery of amyloid‐β1‐42 (Aβ1‐42). Behavioural assays...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-01, Vol.22 (1), p.111-122
Hauptverfasser:	Postu, Paula Alexandra, Noumedem, Jaures A. K., Cioanca, Oana, Hancianu, Monica, Mihasan, Marius, Ciorpac, Mitica, Gorgan, Dragos Lucian, Petre, Brindusa Alina, Hritcu, Lucian
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Alzheimer's disease amyloid antioxidant Antioxidants Brain-derived neurotrophic factor Cognitive ability Copy number dementia Dementia disorders Hippocampus IL‐1β Interleukin 1 Lactuca Lactuca capensis extract Memory mRNA Neurodegenerative diseases Original Rats Rodents
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