Apoptosis induction of colorectal cancer cells HTL-9 in vitro by the transformed products of soybean isoflavones by Ganoderma lucidum

Soybean isoflavones have been one of the potential preventive candidates for antitumor research in recent years. In this paper, we first studied the transformation of soybean isoflavones with the homogenized slurry of Ganoderma lucidum. The resultant transformed products (TSI) contained (703.21±4.35...

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Veröffentlicht in:	Journal of Zhejiang University. B. Science 2017-12, Vol.18 (12), p.1101-1112
Hauptverfasser:	Cui, Mei-lin, Yang, Huan-yi, He, Guo-qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents - chemistry Antitumor activity Apoptosis Bioactive compounds Biocompatibility Biomedical and Life Sciences Biomedicine Breast cancer Cancer Caspase Caspase-3 Caspase-8 Cell Line, Tumor Cell Proliferation Cell Survival Chromatography, High Pressure Liquid Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Cytochrome Cytochrome c Cytotoxicity Daidzein Epithelial cells G1 Phase Ganoderma - metabolism Ganoderma lucidum Gene expression Gene regulation Genetic transformation Genistein Glycine max Glycine max - chemistry Humans Isoflavones Isoflavones - chemistry MCF-7 Cells Medicine, Chinese Traditional Metabolites Mitochondria Mushrooms NF-κB protein p53 Protein Plant Extracts - pharmacology Polymerase chain reaction Signal Transduction - drug effects Slurries Soy products Soybeans Survivin Toxicity Viability
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