Pigmented Squamous Cell Carcinoma In Situ: Report of a New Case and Review of the Literature
Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful bla...
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Veröffentlicht in: | Journal of clinical and experimental dentistry 2017-11, Vol.9 (11), p.e1362-e1365 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful black and red lesion located on the right aspect of the oropharyngeal isthmus. After incisional biopsy, the resulting sample was described as a pigmented squamous cell carcinoma in situ, a diagnosis further confirmed by immunohistochemical analysis. Treatment consisted in total excision of the lesion, and no recurrence was observed after a 30-month follow-up. Clinicians and pathologists should be aware of PSCCIS as a differential diagnosis of melanoma, a lesion which significantly increases the morbidity and mortality rates among these patients.
Pigmented squamous cell carcinoma in situ; oropharyngeal mucosa; immunohistochemistry. |
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ISSN: | 1989-5488 1989-5488 |
DOI: | 10.4317/jced.54053 |