Pigmented Squamous Cell Carcinoma In Situ: Report of a New Case and Review of the Literature

Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful bla...

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Veröffentlicht in:Journal of clinical and experimental dentistry 2017-11, Vol.9 (11), p.e1362-e1365
Hauptverfasser: Martins, Fabiana, Mistro, Florence-Zumbaio, Kignel, Sergio, Palmieri, Michelle, do Canto, Alan-Motta, Braz-Silva, Paulo-Henrique
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Sprache:eng
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Zusammenfassung:Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful black and red lesion located on the right aspect of the oropharyngeal isthmus. After incisional biopsy, the resulting sample was described as a pigmented squamous cell carcinoma in situ, a diagnosis further confirmed by immunohistochemical analysis. Treatment consisted in total excision of the lesion, and no recurrence was observed after a 30-month follow-up. Clinicians and pathologists should be aware of PSCCIS as a differential diagnosis of melanoma, a lesion which significantly increases the morbidity and mortality rates among these patients. Pigmented squamous cell carcinoma in situ; oropharyngeal mucosa; immunohistochemistry.
ISSN:1989-5488
1989-5488
DOI:10.4317/jced.54053