BAP1 mutations in high-grade meningioma: implications for patient care

We have recently shown that the breast cancer (BRCA)1-associated protein-1 tumor suppressor gene (BAP1) is inactivated in a subset of clinically aggressive meningiomas that display rhabdoid histomorphology. Immunohistochemistry for BAP1 protein provides a rapid and inexpensive method for screening s...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2017-10, Vol.19 (11), p.1447-1456
Hauptverfasser:	Shankar, Ganesh M, Santagata, Sandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Meningeal Neoplasms - drug therapy Meningeal Neoplasms - genetics Meningeal Neoplasms - pathology Meningioma - drug therapy Meningioma - genetics Meningioma - pathology Mutation Neoplasm Grading Patient Care - standards Reviews Tumor Suppressor Proteins - genetics Ubiquitin Thiolesterase - genetics
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