Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy

Previous studies suggest that leptin (LEP) has an important role in glucose metabolism in the nonpregnant state. During pregnancy, circulating maternal concentrations of leptin rise significantly, mainly due to increased secretion of leptin from maternal adipose tissue and placenta. This study aimed...

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Veröffentlicht in:	Scientific reports 2017-12, Vol.7 (1), p.17710-8, Article 17710
Hauptverfasser:	Lin, Rong, Ju, Hongfang, Yuan, Ziyu, Zhang, Caicai, Zeng, Liangliang, Sun, Yuantian, Su, Zhenyu, Jin, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	45 45/22 45/77 631/208/205 692/308/2056 692/499 Adipose tissue Adult Asian Continental Ancestry Group - genetics Beta cells Blood Glucose - analysis Blood Glucose - metabolism China Ethnic Groups - genetics Fasting Female Fetus - metabolism Fetuses Gestation Glucose Glucose - metabolism Homeostasis Humanities and Social Sciences Humans Insulin Insulin - analysis Insulin - blood Insulin Resistance - genetics Insulin-Secreting Cells - metabolism Leptin Leptin - genetics Leptin - physiology Maternal-Fetal Exchange - genetics Metabolism multidisciplinary Phenotype Placenta Placenta - metabolism Pregnancy Prenatal Care Science Science (multidisciplinary) Secretion
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