A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: a case–control study

ObjectiveTo compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital.DesignWe employed a case–control study design and recruited dental outpatients into routine serum-based and oral rapid testing grou...

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Veröffentlicht in:BMJ open 2017-06, Vol.7 (6), p.e014601-e014601
Hauptverfasser: Li, Shifu, Su, Shu, Li, Shunxiang, Gao, Liangmin, Cai, Ying, Fu, Jincui, Guo, Chunyuan, Lu, Wei, Cheng, Feng, Jing, Jun, Chen, Liang, Zhang, Lei
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container_title BMJ open
container_volume 7
creator Li, Shifu
Su, Shu
Li, Shunxiang
Gao, Liangmin
Cai, Ying
Fu, Jincui
Guo, Chunyuan
Lu, Wei
Cheng, Feng
Jing, Jun
Chen, Liang
Zhang, Lei
description ObjectiveTo compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital.DesignWe employed a case–control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups.SettingA dental outpatient clinic in the Yuxi People's Hospital, Yunnan.ParticipantsA total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively.ResultsThe percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, χ2=186.4, p
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We compared the acceptance, completion and result notification rate between groups.SettingA dental outpatient clinic in the Yuxi People's Hospital, Yunnan.ParticipantsA total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively.ResultsThe percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, χ2=186.4, p&lt;0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (χ2=77.5, p&lt;0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (χ2=34.6, p&lt;0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p&lt;0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%.ConclusionOral rapid HIV testing is a feasible and efficient approach in a clinical setting.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2016-014601</identifier><identifier>PMID: 28667206</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Acquired immune deficiency syndrome ; Adolescent ; Adult ; AIDS ; Case-Control Studies ; China ; Counseling ; Dental Clinics ; Developing Countries ; Female ; HIV ; HIV Infections - blood ; HIV Infections - diagnosis ; HIV/AIDS ; Hospitals ; Human immunodeficiency virus ; Humans ; LDCs ; Male ; Mass Screening - statistics &amp; numerical data ; Medical tests ; Middle Aged ; Patient Acceptance of Health Care - psychology ; Patient Acceptance of Health Care - statistics &amp; numerical data ; Patient satisfaction ; Point-of-Care Testing - statistics &amp; numerical data ; Population ; Time Factors ; Young Adult</subject><ispartof>BMJ open, 2017-06, Vol.7 (6), p.e014601-e014601</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2017 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b472t-323e283e03d0702466387fa312861d30ae5304906e6f8c30d1d1b2952b9f5e533</citedby><cites>FETCH-LOGICAL-b472t-323e283e03d0702466387fa312861d30ae5304906e6f8c30d1d1b2952b9f5e533</cites><orcidid>0000-0003-2343-084X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bmjopen.bmj.com/content/7/6/e014601.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttp://bmjopen.bmj.com/content/7/6/e014601.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27548,27549,27923,27924,53790,53792,77372,77403</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28667206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Shifu</creatorcontrib><creatorcontrib>Su, Shu</creatorcontrib><creatorcontrib>Li, Shunxiang</creatorcontrib><creatorcontrib>Gao, Liangmin</creatorcontrib><creatorcontrib>Cai, Ying</creatorcontrib><creatorcontrib>Fu, Jincui</creatorcontrib><creatorcontrib>Guo, Chunyuan</creatorcontrib><creatorcontrib>Lu, Wei</creatorcontrib><creatorcontrib>Cheng, Feng</creatorcontrib><creatorcontrib>Jing, Jun</creatorcontrib><creatorcontrib>Chen, Liang</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><title>A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: a case–control study</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><description>ObjectiveTo compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital.DesignWe employed a case–control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups.SettingA dental outpatient clinic in the Yuxi People's Hospital, Yunnan.ParticipantsA total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively.ResultsThe percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, χ2=186.4, p&lt;0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (χ2=77.5, p&lt;0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (χ2=34.6, p&lt;0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p&lt;0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%.ConclusionOral rapid HIV testing is a feasible and efficient approach in a clinical setting.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adolescent</subject><subject>Adult</subject><subject>AIDS</subject><subject>Case-Control Studies</subject><subject>China</subject><subject>Counseling</subject><subject>Dental Clinics</subject><subject>Developing Countries</subject><subject>Female</subject><subject>HIV</subject><subject>HIV Infections - blood</subject><subject>HIV Infections - diagnosis</subject><subject>HIV/AIDS</subject><subject>Hospitals</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>LDCs</subject><subject>Male</subject><subject>Mass Screening - statistics &amp; numerical data</subject><subject>Medical tests</subject><subject>Middle Aged</subject><subject>Patient Acceptance of Health Care - psychology</subject><subject>Patient Acceptance of Health Care - statistics &amp; numerical data</subject><subject>Patient satisfaction</subject><subject>Point-of-Care Testing - statistics &amp; numerical data</subject><subject>Population</subject><subject>Time Factors</subject><subject>Young Adult</subject><issn>2044-6055</issn><issn>2044-6055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNks9qFTEUxgex2FL7BIIE3Ljo1PyfOy6EclFbKNSFCq5CJnOmzWUmGZOZane-g0_iK_kknuFea3VlFkng-50vOYevKJ4wesKY0C-aYRNHCCWnTJeUSU3Zg-KAUylLTZV6eO--XxzlvKG4pKqV4o-Kfb7SuuJUHxQ_TomLw2iTzzGQ2BHoOnCTv4EAOZMGpi8AKCTbk2RH35IJ8uTDFbGhJSnOeAeSIc1D2dgMf_QuJnJ2_pH4gChBcLSThzCRFjd0c70P3i3yp_mrJ-8SLA_PCY7J-toH-5JY4tDx57fvLoYpxZ7kaW5vHxd7ne0zHO3Ow-LDm9fv12flxeXb8_XpRdnIik-l4AL4SgAVLa0ol1qLVdVZwbB31gpqQQkqa6pBdysnaMta1vBa8abuFGrisHi19R3nZoDW4a9xCGZMfrDp1kTrzd9K8NfmKt4YVQmpqhoNnu8MUvw841TM4LODvrcB4pwNq5kSUiu5vPXsH3QT5xSwvYWStWarSiMltpRLMWec191nGDVLKswuFWZJhdmmAque3u_jruZ3BhA42QJY_V-OvwBSFsa2</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Li, Shifu</creator><creator>Su, Shu</creator><creator>Li, Shunxiang</creator><creator>Gao, Liangmin</creator><creator>Cai, Ying</creator><creator>Fu, Jincui</creator><creator>Guo, Chunyuan</creator><creator>Lu, Wei</creator><creator>Cheng, Feng</creator><creator>Jing, Jun</creator><creator>Chen, Liang</creator><creator>Zhang, Lei</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2343-084X</orcidid></search><sort><creationdate>20170601</creationdate><title>A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: a case–control study</title><author>Li, Shifu ; Su, Shu ; Li, Shunxiang ; Gao, Liangmin ; Cai, Ying ; Fu, Jincui ; Guo, Chunyuan ; Lu, Wei ; Cheng, Feng ; Jing, Jun ; Chen, Liang ; Zhang, Lei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b472t-323e283e03d0702466387fa312861d30ae5304906e6f8c30d1d1b2952b9f5e533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Adolescent</topic><topic>Adult</topic><topic>AIDS</topic><topic>Case-Control Studies</topic><topic>China</topic><topic>Counseling</topic><topic>Dental Clinics</topic><topic>Developing Countries</topic><topic>Female</topic><topic>HIV</topic><topic>HIV Infections - blood</topic><topic>HIV Infections - diagnosis</topic><topic>HIV/AIDS</topic><topic>Hospitals</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>LDCs</topic><topic>Male</topic><topic>Mass Screening - statistics &amp; numerical data</topic><topic>Medical tests</topic><topic>Middle Aged</topic><topic>Patient Acceptance of Health Care - psychology</topic><topic>Patient Acceptance of Health Care - statistics &amp; numerical data</topic><topic>Patient satisfaction</topic><topic>Point-of-Care Testing - statistics &amp; numerical data</topic><topic>Population</topic><topic>Time Factors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Shifu</creatorcontrib><creatorcontrib>Su, Shu</creatorcontrib><creatorcontrib>Li, Shunxiang</creatorcontrib><creatorcontrib>Gao, Liangmin</creatorcontrib><creatorcontrib>Cai, Ying</creatorcontrib><creatorcontrib>Fu, Jincui</creatorcontrib><creatorcontrib>Guo, Chunyuan</creatorcontrib><creatorcontrib>Lu, Wei</creatorcontrib><creatorcontrib>Cheng, Feng</creatorcontrib><creatorcontrib>Jing, Jun</creatorcontrib><creatorcontrib>Chen, Liang</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><collection>BMJ Journals (Open Access)</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Health &amp; 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Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Consumer Database (Proquest)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Shifu</au><au>Su, Shu</au><au>Li, Shunxiang</au><au>Gao, Liangmin</au><au>Cai, Ying</au><au>Fu, Jincui</au><au>Guo, Chunyuan</au><au>Lu, Wei</au><au>Cheng, Feng</au><au>Jing, Jun</au><au>Chen, Liang</au><au>Zhang, Lei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: a case–control study</atitle><jtitle>BMJ open</jtitle><addtitle>BMJ Open</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>7</volume><issue>6</issue><spage>e014601</spage><epage>e014601</epage><pages>e014601-e014601</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>ObjectiveTo compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital.DesignWe employed a case–control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups.SettingA dental outpatient clinic in the Yuxi People's Hospital, Yunnan.ParticipantsA total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively.ResultsThe percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, χ2=186.4, p&lt;0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (χ2=77.5, p&lt;0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (χ2=34.6, p&lt;0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p&lt;0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%.ConclusionOral rapid HIV testing is a feasible and efficient approach in a clinical setting.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>28667206</pmid><doi>10.1136/bmjopen-2016-014601</doi><orcidid>https://orcid.org/0000-0003-2343-084X</orcidid><oa>free_for_read</oa></addata></record>
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subjects Acquired immune deficiency syndrome
Adolescent
Adult
AIDS
Case-Control Studies
China
Counseling
Dental Clinics
Developing Countries
Female
HIV
HIV Infections - blood
HIV Infections - diagnosis
HIV/AIDS
Hospitals
Human immunodeficiency virus
Humans
LDCs
Male
Mass Screening - statistics & numerical data
Medical tests
Middle Aged
Patient Acceptance of Health Care - psychology
Patient Acceptance of Health Care - statistics & numerical data
Patient satisfaction
Point-of-Care Testing - statistics & numerical data
Population
Time Factors
Young Adult
title A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: a case–control study
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