2‑Arylidene Hydrazinecarbodithioates as Potent, Selective Inhibitors of Cystathionine γ‑Lyase (CSE)

Hydrogen sulfide is produced from l-cysteine by the action of both cystathionine γ-lyase (CSE) and cystathionine β-synthase (CBS) and increasingly has been found to play a profound regulatory role in a range of physiological processes. Mounting evidence suggests that upregulation of hydrogen sulfide...

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Veröffentlicht in:	ACS medicinal chemistry letters 2017-12, Vol.8 (12), p.1241-1245
Hauptverfasser:	Bhattacharjee, Abir, Sinha, Antara, Ratia, Kiira, Yin, Liang, Delgado-Rivera, Loruhama, Petukhov, Pavel A, Thatcher, Gregory R. J, Wardrop, Duncan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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