Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway

Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa B (NF-κB)-mediated inflammatory pathway and pregnane X...

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Veröffentlicht in:	Oncotarget 2017-11, Vol.8 (61), p.102974-102988
Hauptverfasser:	He, Liuqin, Li, Huan, Huang, Niu, Zhou, Xihong, Tian, Junquan, Li, Tiejun, Wu, Jing, Tian, Yanan, Yin, Yulong, Yao, Kang
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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