Delineating the distinct role of AKT in mediating cell survival and proliferation induced by CD154 and IL-4/IL-21 in chronic lymphocytic leukemia

The functional significance of AKT in chronic lymphocytic leukemia (CLL) remains unclear. Given the importance of non-malignant T cells in regulating clonal expansion in CLL, we investigated the role of AKT in T cell-mediated cytoprotection and proliferation using an established co-culture system in...

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Veröffentlicht in:	Oncotarget 2017-11, Vol.8 (61), p.102948-102964
Hauptverfasser:	Chapman, Elinor A, Oates, Melanie, Mohammad, Ishaque S, Davies, Barry R, Stockman, Paul K, Zhuang, Jianguo, Pettitt, Andrew R
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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