Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis
Patients undergoing radiation therapy for the head and neck are susceptible to a significant and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy include but are not limited to an increased susceptibility to dental caries and periodontal disease. They also i...
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description | Patients undergoing radiation therapy for the head and neck are susceptible to a significant and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy include but are not limited to an increased susceptibility to dental caries and periodontal disease. They also include profound and often permanent functional and sensory changes involving the oral soft tissue. These changes range from oral mucositis experienced during and soon after treatment, mucosal opportunistic infections, neurosensory disorders, and tissue fibrosis. Many of the oral soft tissue changes following radiation therapy are difficult challenges to the patients and their caregivers and require life‐long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. We discuss the presentation, prognosis, and management strategies of the dental structure and oral soft tissue morbidities resulting from the administration of therapeutic radiation in head and neck patient. A case for a collaborative and integrated multidisciplinary approach to the management of these patients is made, with specific recommendation to include knowledgeable and experienced oral health care professionals in the treatment team.
Oral complications of radiation therapy to the head and neck can result in acute and long‐term deterioration in oral soft tissues and dentition. The presentation, prognosis, and strategies to manage the dental and nondental morbidities of radiation therapy to the head and neck are discussed in this manuscript. |
doi_str_mv | 10.1002/cam4.1221 |
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Oral complications of radiation therapy to the head and neck can result in acute and long‐term deterioration in oral soft tissues and dentition. The presentation, prognosis, and strategies to manage the dental and nondental morbidities of radiation therapy to the head and neck are discussed in this manuscript.</description><identifier>ISSN: 2045-7634</identifier><identifier>EISSN: 2045-7634</identifier><identifier>DOI: 10.1002/cam4.1221</identifier><identifier>PMID: 29071801</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Clinical Cancer Research ; Communicable Diseases - diagnosis ; Communicable Diseases - etiology ; Communicable Diseases - therapy ; Dental caries ; Dental Caries - diagnosis ; Dental Caries - etiology ; Dental Caries - therapy ; Fibrosis ; Gum disease ; Head & neck cancer ; head and neck cancer ; Head and Neck Neoplasms - pathology ; Head and Neck Neoplasms - radiotherapy ; Humans ; neurosensory disorder ; oral candidiasis ; oral health ; Oral hygiene ; oral mucositis ; Osteoradionecrosis - diagnosis ; Osteoradionecrosis - etiology ; Osteoradionecrosis - therapy ; Periodontal Diseases - diagnosis ; Periodontal Diseases - etiology ; Periodontal Diseases - therapy ; Periodontics ; Radiation therapy ; Radiotherapy - adverse effects ; Review ; Risk Factors ; Salivation - radiation effects ; Sensation Disorders - diagnosis ; Sensation Disorders - etiology ; Sensation Disorders - physiopathology ; Sensation Disorders - therapy ; Stomatitis - diagnosis ; Stomatitis - etiology ; Stomatitis - therapy ; Treatment Outcome</subject><ispartof>Cancer medicine (Malden, MA), 2017-12, Vol.6 (12), p.2918-2931</ispartof><rights>2017 The Authors. published by John Wiley & Sons Ltd.</rights><rights>2017 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.</rights><rights>2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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The oral morbidities of radiation therapy include but are not limited to an increased susceptibility to dental caries and periodontal disease. They also include profound and often permanent functional and sensory changes involving the oral soft tissue. These changes range from oral mucositis experienced during and soon after treatment, mucosal opportunistic infections, neurosensory disorders, and tissue fibrosis. Many of the oral soft tissue changes following radiation therapy are difficult challenges to the patients and their caregivers and require life‐long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. We discuss the presentation, prognosis, and management strategies of the dental structure and oral soft tissue morbidities resulting from the administration of therapeutic radiation in head and neck patient. A case for a collaborative and integrated multidisciplinary approach to the management of these patients is made, with specific recommendation to include knowledgeable and experienced oral health care professionals in the treatment team.
Oral complications of radiation therapy to the head and neck can result in acute and long‐term deterioration in oral soft tissues and dentition. The presentation, prognosis, and strategies to manage the dental and nondental morbidities of radiation therapy to the head and neck are discussed in this manuscript.</description><subject>Clinical Cancer Research</subject><subject>Communicable Diseases - diagnosis</subject><subject>Communicable Diseases - etiology</subject><subject>Communicable Diseases - therapy</subject><subject>Dental caries</subject><subject>Dental Caries - diagnosis</subject><subject>Dental Caries - etiology</subject><subject>Dental Caries - therapy</subject><subject>Fibrosis</subject><subject>Gum disease</subject><subject>Head & neck cancer</subject><subject>head and neck cancer</subject><subject>Head and Neck Neoplasms - pathology</subject><subject>Head and Neck Neoplasms - radiotherapy</subject><subject>Humans</subject><subject>neurosensory disorder</subject><subject>oral candidiasis</subject><subject>oral health</subject><subject>Oral hygiene</subject><subject>oral mucositis</subject><subject>Osteoradionecrosis - 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The oral morbidities of radiation therapy include but are not limited to an increased susceptibility to dental caries and periodontal disease. They also include profound and often permanent functional and sensory changes involving the oral soft tissue. These changes range from oral mucositis experienced during and soon after treatment, mucosal opportunistic infections, neurosensory disorders, and tissue fibrosis. Many of the oral soft tissue changes following radiation therapy are difficult challenges to the patients and their caregivers and require life‐long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. We discuss the presentation, prognosis, and management strategies of the dental structure and oral soft tissue morbidities resulting from the administration of therapeutic radiation in head and neck patient. A case for a collaborative and integrated multidisciplinary approach to the management of these patients is made, with specific recommendation to include knowledgeable and experienced oral health care professionals in the treatment team.
Oral complications of radiation therapy to the head and neck can result in acute and long‐term deterioration in oral soft tissues and dentition. The presentation, prognosis, and strategies to manage the dental and nondental morbidities of radiation therapy to the head and neck are discussed in this manuscript.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>29071801</pmid><doi>10.1002/cam4.1221</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0001-7484-3631</orcidid><orcidid>https://orcid.org/0000-0003-3447-299X</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Clinical Cancer Research Communicable Diseases - diagnosis Communicable Diseases - etiology Communicable Diseases - therapy Dental caries Dental Caries - diagnosis Dental Caries - etiology Dental Caries - therapy Fibrosis Gum disease Head & neck cancer head and neck cancer Head and Neck Neoplasms - pathology Head and Neck Neoplasms - radiotherapy Humans neurosensory disorder oral candidiasis oral health Oral hygiene oral mucositis Osteoradionecrosis - diagnosis Osteoradionecrosis - etiology Osteoradionecrosis - therapy Periodontal Diseases - diagnosis Periodontal Diseases - etiology Periodontal Diseases - therapy Periodontics Radiation therapy Radiotherapy - adverse effects Review Risk Factors Salivation - radiation effects Sensation Disorders - diagnosis Sensation Disorders - etiology Sensation Disorders - physiopathology Sensation Disorders - therapy Stomatitis - diagnosis Stomatitis - etiology Stomatitis - therapy Treatment Outcome |
title | Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis |
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