The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages

Müllerian inhibiting substance, also called anti-Müllerian hormone (AMH), inhibits proliferation and induces apoptosis of AMH type II receptor-positive tumor cells, such as human ovarian cancers (OCs). On this basis, a humanized glyco-engineered monoclonal antibody (3C23K) has been developed. The ai...

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Veröffentlicht in:	Oncotarget 2017-11, Vol.8 (59), p.99950-99965
Hauptverfasser:	Bougherara, Houcine, Némati, Fariba, Nicolas, André, Massonnet, Gérald, Pugnière, Martine, Ngô, Charlotte, Le Frère-Belda, Marie-Aude, Leary, Alexandra, Alexandre, Jérôme, Meseure, Didier, Barret, Jean-Marc, Navarro-Teulon, Isabelle, Pèlegrin, André, Roman-Roman, Sergio, Prost, Jean-François, Donnadieu, Emmanuel, Decaudin, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Gynecology and obstetrics Human health and pathology Immunology Immunotherapy Life Sciences Research Paper
Online-Zugang:	Volltext
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