Diagnosis and Treatment of Progressive Multifocal Leukoencephalopathy Associated with Multiple Sclerosis Therapies

Progressive multifocal leukoencephalopathy (PML) is a rare, but serious, complication encountered in patients treated with a select number of disease-modifying therapies (DMTs) utilized in treating multiple sclerosis (MS). PML results from a viral infection in the brain for which the only demonstrat...

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Veröffentlicht in:	Neurotherapeutics 2017-10, Vol.14 (4), p.961-973
Hauptverfasser:	Williamson, Eric M. L., Berger, Joseph R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - therapeutic use Biomedical and Life Sciences Biomedicine Encephalitis Humans Immune system Immunologic Factors - adverse effects Immunosuppressive Agents - adverse effects Immunotherapy JC Virus - immunology JC Virus - physiology Leukoencephalopathy Leukoencephalopathy, Progressive Multifocal - diagnosis Leukoencephalopathy, Progressive Multifocal - immunology Leukoencephalopathy, Progressive Multifocal - therapy Leukoencephalopathy, Progressive Multifocal - virology Medical diagnosis Monoclonal antibodies Morbidity Multiple sclerosis Multiple Sclerosis - therapy Natalizumab - adverse effects Neurobiology Neurology Neurosciences Neurosurgery Progressive multifocal leukoencephalopathy Review Risk factors Viral infections
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