Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics
Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of...
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Veröffentlicht in: | Neurotherapeutics 2017-10, Vol.14 (4), p.945-951 |
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creator | Amezcua, Lilyana Nelson, Flavia |
description | Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed. |
doi_str_mv | 10.1007/s13311-017-0560-9 |
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While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed.</description><identifier>ISSN: 1933-7213</identifier><identifier>ISSN: 1878-7479</identifier><identifier>EISSN: 1878-7479</identifier><identifier>DOI: 10.1007/s13311-017-0560-9</identifier><identifier>PMID: 28779373</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Ethics ; Humans ; Medical ethics ; Multiple sclerosis ; Multiple Sclerosis - economics ; Multiple Sclerosis - therapy ; Naltrexone ; Neurobiology ; Neurology ; Neurosciences ; Neurosurgery ; Patient Participation ; Review ; Reviews ; Stem cells ; Translational Research, Biomedical - economics ; Translational Research, Biomedical - ethics</subject><ispartof>Neurotherapeutics, 2017-10, Vol.14 (4), p.945-951</ispartof><rights>The American Society for Experimental NeuroTherapeutics, Inc. 2017</rights><rights>Neurotherapeutics is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-5f0b70ade6322bfcf6085b9ef17dae3e2e5b7e20b096075cecbb2c05785f37033</citedby><cites>FETCH-LOGICAL-c470t-5f0b70ade6322bfcf6085b9ef17dae3e2e5b7e20b096075cecbb2c05785f37033</cites><orcidid>0000-0003-1542-7819</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722765/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722765/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,41493,42562,51324,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28779373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Amezcua, Lilyana</creatorcontrib><creatorcontrib>Nelson, Flavia</creatorcontrib><title>Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics</title><title>Neurotherapeutics</title><addtitle>Neurotherapeutics</addtitle><addtitle>Neurotherapeutics</addtitle><description>Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Ethics</subject><subject>Humans</subject><subject>Medical ethics</subject><subject>Multiple sclerosis</subject><subject>Multiple Sclerosis - economics</subject><subject>Multiple Sclerosis - therapy</subject><subject>Naltrexone</subject><subject>Neurobiology</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Patient Participation</subject><subject>Review</subject><subject>Reviews</subject><subject>Stem cells</subject><subject>Translational Research, Biomedical - economics</subject><subject>Translational Research, Biomedical - ethics</subject><issn>1933-7213</issn><issn>1878-7479</issn><issn>1878-7479</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kVFrFTEQhYMotlZ_gC-y4Isv0Umy2dm8CHJpVago2j6HbHbSm7J3c012C_57U24tVfApB-abk5k5jL0U8FYA4LsilBKCg0AOugNuHrFj0WPPsUXzuGqjFEcp1BF7Vso1gFbK9E_ZkewRjUJ1zC5Pl230bmo2aS5xpOyWWFWTQvOtSpoXfrbOI43Ndyrkst82IeXmyzotcT9R88NPlFOJpbnY1uY9rUv05Tl7EtxU6MXde8Iuz04vNp_4-dePnzcfzrlvERauAwwIbqROSTkEHzro9WAoCBwdKZKkByQJA5gOUHvywyA9aOx1UAhKnbD3B9_9Ouxo9HXc7Ca7z3Hn8i-bXLR_V-a4tVfpxmqUEjtdDd7cGeT0c6Wy2F0snqbJzZTWYoWRXddjK9qKvv4HvU5rnut6lcJWK0DASokD5etVSqZwP4wAexuaPYRma2j2NjRras-rh1vcd_xJqQLyAJRamq8oP_j6v66_Aa7Fo6s</recordid><startdate>20171001</startdate><enddate>20171001</enddate><creator>Amezcua, Lilyana</creator><creator>Nelson, Flavia</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1542-7819</orcidid></search><sort><creationdate>20171001</creationdate><title>Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics</title><author>Amezcua, Lilyana ; Nelson, Flavia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-5f0b70ade6322bfcf6085b9ef17dae3e2e5b7e20b096075cecbb2c05785f37033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Ethics</topic><topic>Humans</topic><topic>Medical ethics</topic><topic>Multiple sclerosis</topic><topic>Multiple Sclerosis - economics</topic><topic>Multiple Sclerosis - therapy</topic><topic>Naltrexone</topic><topic>Neurobiology</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Patient Participation</topic><topic>Review</topic><topic>Reviews</topic><topic>Stem cells</topic><topic>Translational Research, Biomedical - economics</topic><topic>Translational Research, Biomedical - ethics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Amezcua, Lilyana</creatorcontrib><creatorcontrib>Nelson, Flavia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Neurotherapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Amezcua, Lilyana</au><au>Nelson, Flavia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics</atitle><jtitle>Neurotherapeutics</jtitle><stitle>Neurotherapeutics</stitle><addtitle>Neurotherapeutics</addtitle><date>2017-10-01</date><risdate>2017</risdate><volume>14</volume><issue>4</issue><spage>945</spage><epage>951</epage><pages>945-951</pages><issn>1933-7213</issn><issn>1878-7479</issn><eissn>1878-7479</eissn><abstract>Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. 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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; SpringerLink Journals - AutoHoldings |
subjects | Biomedical and Life Sciences Biomedicine Ethics Humans Medical ethics Multiple sclerosis Multiple Sclerosis - economics Multiple Sclerosis - therapy Naltrexone Neurobiology Neurology Neurosciences Neurosurgery Patient Participation Review Reviews Stem cells Translational Research, Biomedical - economics Translational Research, Biomedical - ethics |
title | Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics |
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