Assessing the Role of Inhibition in Stabilizing Neocortical Networks Requires Large-Scale Perturbation of the Inhibitory Population

Neurons within cortical microcircuits are interconnected with recurrent excitatory synaptic connections that are thought to amplify signals (Douglas and Martin, 2007), form selective subnetworks (Ko et al., 2011), and aid feature discrimination. Strong inhibition (Haider et al., 2013) counterbalance...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of neuroscience 2017-12, Vol.37 (49), p.12050-12067
Hauptverfasser:	Sadeh, Sadra, Silver, R Angus, Mrsic-Flogel, Thomas D, Muir, Dylan Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Computational neuroscience Counterbalances Excitation Humans Inhibition Mathematical models Neocortex - physiology Nerve Net - physiology Networks Neural Inhibition - physiology Neurons Somatosensory cortex Synapses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!