Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging

Dl-3-n-butylphthalide (NBP) is a drug that is used in the treatment of ischaemic stroke. However, to the best of our knowledge, there are no systematic studies investigating the effects of dl-3-n-butylphtalide on the brain metabolism of small molecules. In this study, we first investigated the effec...

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Veröffentlicht in:	International journal of molecular sciences 2017-11, Vol.18 (11), p.2451
Hauptverfasser:	Liu, Run-Zhe, Fan, Chao-Xin, Zhang, Zhi-Lin, Zhao, Xin, Sun, Yi, Liu, Hui-Hui, Nie, Zong-Xiu, Pu, Xiao-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Ascorbic acid Brain Cerebral blood flow Cerebral infarction Desorption Glucose metabolism Glutamine Homeostasis Imaging Infarction Ionization Ions Ischemia Liquid chromatography Malate Mass spectrometry Mass spectroscopy Metabolism Metabolites N-Acetylaspartate Neuroimaging Occlusion Oxidative stress Rats Rodents Scientific imaging Spatial distribution Spectroscopy Stroke Studies
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