Association Between Motor Symptoms and Brain Metabolism in Early Huntington Disease

IMPORTANCE: Brain hypometabolism is associated with the clinical consequences of the degenerative process, but little is known about regional hypermetabolism, sometimes observed in the brain of patients with clinically manifest Huntington disease (HD). Studying the role of regional hypermetabolism i...

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Veröffentlicht in:	JAMA neurology 2017-09, Vol.74 (9), p.1088-1096
Hauptverfasser:	Gaura, Véronique, Lavisse, Sonia, Payoux, Pierre, Goldman, Serge, Verny, Christophe, Krystkowiak, Pierre, Damier, Philippe, Supiot, Frédéric, Bachoud-Levi, Anne-Catherine, Remy, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cerebellar Nuclei - diagnostic imaging Cerebellar Nuclei - metabolism Cerebellum - diagnostic imaging Cerebellum - metabolism Cerebral Cortex - diagnostic imaging Cerebral Cortex - metabolism Cross-Sectional Studies Female Human health and pathology Humans Huntington Disease - complications Huntington Disease - diagnostic imaging Huntington Disease - metabolism Hyperkinesis - diagnostic imaging Hyperkinesis - etiology Hyperkinesis - metabolism Hypokinesia - diagnostic imaging Hypokinesia - etiology Hypokinesia - metabolism Life Sciences Male Middle Aged Online First Original Investigation
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