Administration of signalling molecules dictates stem cell homing for in situ regeneration

Ex vivo‐expanded stem cells have long been a cornerstone of biotherapeutics and have attracted increasing attention for treating intractable diseases and improving tissue regeneration. However, using exogenous cellular materials to develop restorative treatments for large numbers of patients has bec...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2017-12, Vol.21 (12), p.3162-3177
Hauptverfasser:	Li, Xuan, He, Xiao‐Tao, Yin, Yuan, Wu, Rui‐Xin, Tian, Bei‐Min, Chen, Fa‐Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials - therapeutic use Biomaterials cell modification Cell Movement Cell- and Tissue-Based Therapy - methods Chemokines Chemotactic Factors - therapeutic use controlled release Homing Humans Immunomodulation in situ tissue engineering Inflammation Intercellular Signaling Peptides and Proteins - therapeutic use Regeneration - drug effects Regeneration - physiology Review Reviews Signal Transduction stem cell homing Stem Cell Transplantation Stem cells Stem Cells - cytology Stem Cells - drug effects Stem Cells - metabolism Tissue engineering Tissue Engineering - methods Wound healing
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