Semisynthetic Bioluminescent Sensor Proteins for Direct Detection of Antibodies and Small Molecules in Solution

Single-step immunoassays that can be performed directly in solution are ideally suited for point-of-care diagnostics. Our group recently developed a new platform of bioluminescent sensor proteins (LUMABS; LUMinescent AntiBody Sensor) that allow antibody detection in blood plasma. Thus far, LUMABS ha...

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Veröffentlicht in:	ACS sensors 2017-11, Vol.2 (11), p.1730-1736
Hauptverfasser:	Arts, Remco, Ludwig, Susann K. J., van Gerven, Benice C. B., Estirado, Eva Magdalena, Milroy, Lech-Gustav, Merkx, Maarten
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemistry Antibodies - immunology Azides - chemistry Creatinine - analysis Creatinine - immunology Dinitrophenols - analysis Dinitrophenols - immunology Epitopes - chemistry Epitopes - immunology Immunoassay - methods Luminescent Proteins - chemistry Phenylalanine - analogs & derivatives Phenylalanine - chemistry Solutions
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