Cholesterol depletion does not alter the capacitance or Ca handling of the surface or t‐tubule membranes in mouse ventricular myocytes

Cholesterol is a key component of the cell plasma membrane. It has been suggested that the t‐tubule membrane of cardiac ventricular myocytes is enriched in cholesterol and that this plays a role in determining t‐tubule structure and function. We have used methyl‐β‐cyclodextrin (MβCD) to deplete chol...

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Veröffentlicht in:Physiological reports 2017-11, Vol.5 (22), p.n/a
Hauptverfasser: Gadeberg, Hanne C., Kong, Cherrie H. T., Bryant, Simon M., James, Andrew F., Orchard, Clive H.
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Sprache:eng
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