COG7 deficiency in Drosophila generates multifaceted developmental, behavioral and protein glycosylation phenotypes

Congenital disorders of glycosylation (CDG) comprise a family of human multisystemic diseases caused by recessive mutations in genes required for protein N-glycosylation. More than 100 distinct forms of CDGs have been identified and most of them cause severe neurological impairment. The Conserved Ol...

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Veröffentlicht in:Journal of cell science 2017-11, Vol.130 (21), p.3637-3649
Hauptverfasser: Frappaolo, Anna, Sechi, Stefano, Kumagai, Tadahiro, Robinson, Sarah, Fraschini, Roberta, Karimpour-Ghahnavieh, Angela, Belloni, Giorgio, Piergentili, Roberto, Tiemeyer, Katherine H, Tiemeyer, Michael, Giansanti, Maria Grazia
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Sprache:eng
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