Discordance between imaging and immunohistochemistry in unilateral primary aldosteronism

Summary Objective Correct subtyping of primary aldosteronism (PA) is essential for good surgical outcomes. Adrenal vein sampling (AVS) and/or computed tomography (CT) are used for PA subclassification. Clinical and/or biochemical improvement after surgery, however, is not always achieved in patients...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 2017-12, Vol.87 (6), p.665-672
Hauptverfasser:	Nanba, Aya T., Nanba, Kazutaka, Byrd, James B., Shields, James J., Giordano, Thomas J., Miller, Barbara S., Rainey, William E., Auchus, Richard J., Turcu, Adina F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal glands Adrenal Glands - metabolism Adrenal Glands - pathology Adrenal Glands - surgery adrenal vein sampling Adrenalectomy Adult Aged Aldosterone aldosterone producing adenoma Aldosterone synthase Computed tomography CYP11B2 Cytochrome P-450 CYP11B2 - metabolism Discordance Endocrine disorders Female Humans Hydroxylase Hyperaldosteronism - metabolism Hyperaldosteronism - pathology Hyperaldosteronism - surgery Immunohistochemistry Immunohistochemistry - methods Male Medical imaging Middle Aged Nodules primary aldosteronism Retrospective Studies Sampling Steroid 17-alpha-Hydroxylase - metabolism Surgery Surgical outcomes
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