Life-threatening haemorrhage secondary to nicorandil-induced severe peri-anal ulceration
Nicorandil-induced ulceration is rare but has been reported at multiple sites throughout the gastrointestinal tract. We report a life-threatening complication of such ulceration - catastrophic per-rectal haemorrhage requiring emergency surgery with no prior symptoms. Whilst nicorandil should be cons...
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| Veröffentlicht in: | Annals of the Royal College of Surgeons of England 2010-09, Vol.92 (6), p.W39-e40 |
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| container_title | Annals of the Royal College of Surgeons of England |
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| creator | Mosley, F Bhasin, N Davies, J B Ausobsky, J R |
| description | Nicorandil-induced ulceration is rare but has been reported at multiple sites throughout the gastrointestinal tract. We report a life-threatening complication of such ulceration - catastrophic per-rectal haemorrhage requiring emergency surgery with no prior symptoms. Whilst nicorandil should be considered in cases of chronic peri-anal and peristomal ulceration which fail to respond to conventional treatments, this case highlights its importance in the setting of acute surgical presentations. |
| doi_str_mv | 10.1308/147870810X12699662981519 |
| format | Article |
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We report a life-threatening complication of such ulceration - catastrophic per-rectal haemorrhage requiring emergency surgery with no prior symptoms. 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We report a life-threatening complication of such ulceration - catastrophic per-rectal haemorrhage requiring emergency surgery with no prior symptoms. 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| issn | 0035-8843 1478-7083 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acute Disease Aged Anus Diseases - etiology Fissure in Ano - chemically induced Fissure in Ano - complications Fissure in Ano - surgery Hemorrhage - etiology Humans Male Nicorandil - adverse effects Online Case Report Vasodilator Agents - adverse effects |
| title | Life-threatening haemorrhage secondary to nicorandil-induced severe peri-anal ulceration |
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