The Electron Transport Chain Sensitizes Staphylococcus aureus and Enterococcus faecalis to the Oxidative Burst

Small-colony variants (SCVs) of typically lack a functional electron transport chain and cannot produce virulence factors such as leukocidins, hemolysins, or the antioxidant staphyloxanthin. Despite this, SCVs are associated with persistent infections of the bloodstream, bones, and prosthetic device...

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Veröffentlicht in:	Infection and immunity 2017-12, Vol.85 (12)
Hauptverfasser:	Painter, Kimberley L, Hall, Alex, Ha, Kam Pou, Edwards, Andrew M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism Bacterial Infections Blood - microbiology Blood Bactericidal Activity Electron Transport Enterococcus faecalis - genetics Enterococcus faecalis - physiology Humans Microbial Viability - drug effects Neutrophils - immunology Respiratory Burst Staphylococcus aureus - genetics Staphylococcus aureus - physiology Superoxides - metabolism
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