Invasive Candida Infection after Upper Gastrointestinal Tract Surgery for Gastric Cancer
Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomial Candida peritonitis than lower GIT procedures and they thus constitute an independent risk factor for mortality. Because of the severity of postsurgical fungal infections complications, intensivists and surgeo...
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| Veröffentlicht in: | International Journal of Surgical Oncology 2017-01, Vol.2017 (2017), p.1-7-005 |
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| container_title | International Journal of Surgical Oncology |
| container_volume | 2017 |
| creator | Klein, Moti Peiser, Jochanan G. Frank, Dmitry Koyfman, Leonid Borer, Abraham Kirshtein, Boris Friger, Michael Sebbag, Gilbert Brotfain, Evgeni Bichovsky, Yoav |
| description | Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomial Candida peritonitis than lower GIT procedures and they thus constitute an independent risk factor for mortality. Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer. Invasive fungal infections related to secondary peritonitis following oncologic upper GIT surgery had a higher mortality rate than patients with nonfungal postoperative infectious complications. The presence of gastroesophageal junction leakage and advanced age were found to be independent risk factors for invasive fungal infection after oncologic upper GIT surgery. |
| doi_str_mv | 10.1155/2017/6058567 |
| format | Article |
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Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer. Invasive fungal infections related to secondary peritonitis following oncologic upper GIT surgery had a higher mortality rate than patients with nonfungal postoperative infectious complications. The presence of gastroesophageal junction leakage and advanced age were found to be independent risk factors for invasive fungal infection after oncologic upper GIT surgery.</description><identifier>ISSN: 2090-1402</identifier><identifier>EISSN: 2090-1410</identifier><identifier>DOI: 10.1155/2017/6058567</identifier><identifier>PMID: 29234525</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Limiteds</publisher><subject>Abdomen ; Antifungal agents ; Bacterial infections ; Chronic illnesses ; Complications and side effects ; Confidence intervals ; Diabetes ; Fungal infections ; Gastric cancer ; Gastrointestinal system ; Hospitals ; Infection ; Information systems ; Intensive care ; Laboratories ; Medical centers ; Mortality ; Mycoses ; Nutrition ; Parenteral nutrition ; Peritonitis ; Risk factors ; Statistical analysis ; Stomach cancer ; Studies ; Surgery</subject><ispartof>International Journal of Surgical Oncology, 2017-01, Vol.2017 (2017), p.1-7-005</ispartof><rights>Copyright © 2017 Evgeni Brotfain et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2017 Evgeni Brotfain et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2017 Evgeni Brotfain et al. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a638t-de03f1b694969431c5b36f86c2d5c95a0a59207fb966d0393939c7f6a06f74f13</citedby><cites>FETCH-LOGICAL-a638t-de03f1b694969431c5b36f86c2d5c95a0a59207fb966d0393939c7f6a06f74f13</cites><orcidid>0000-0002-1353-9852 ; 0000-0001-7234-6607</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695031/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695031/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29234525$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Curley, S.</contributor><creatorcontrib>Klein, Moti</creatorcontrib><creatorcontrib>Peiser, Jochanan G.</creatorcontrib><creatorcontrib>Frank, Dmitry</creatorcontrib><creatorcontrib>Koyfman, Leonid</creatorcontrib><creatorcontrib>Borer, Abraham</creatorcontrib><creatorcontrib>Kirshtein, Boris</creatorcontrib><creatorcontrib>Friger, Michael</creatorcontrib><creatorcontrib>Sebbag, Gilbert</creatorcontrib><creatorcontrib>Brotfain, Evgeni</creatorcontrib><creatorcontrib>Bichovsky, Yoav</creatorcontrib><title>Invasive Candida Infection after Upper Gastrointestinal Tract Surgery for Gastric Cancer</title><title>International Journal of Surgical Oncology</title><addtitle>Int J Surg Oncol</addtitle><description>Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomial Candida peritonitis than lower GIT procedures and they thus constitute an independent risk factor for mortality. Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer. Invasive fungal infections related to secondary peritonitis following oncologic upper GIT surgery had a higher mortality rate than patients with nonfungal postoperative infectious complications. 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Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer. Invasive fungal infections related to secondary peritonitis following oncologic upper GIT surgery had a higher mortality rate than patients with nonfungal postoperative infectious complications. 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| source | Wiley Online Library Open Access; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; PubMed Central Open Access |
| subjects | Abdomen Antifungal agents Bacterial infections Chronic illnesses Complications and side effects Confidence intervals Diabetes Fungal infections Gastric cancer Gastrointestinal system Hospitals Infection Information systems Intensive care Laboratories Medical centers Mortality Mycoses Nutrition Parenteral nutrition Peritonitis Risk factors Statistical analysis Stomach cancer Studies Surgery |
| title | Invasive Candida Infection after Upper Gastrointestinal Tract Surgery for Gastric Cancer |
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