Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study
To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital...
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| Veröffentlicht in: | Saudi medical journal 2017-10, Vol.38 (10), p.994-999 |
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| container_title | Saudi medical journal |
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| creator | Mismar, Ayman A Mahseeri, Mohammad I Al-Ghazawi, Mutasim A Obeidat, Firas W Albsoul, Mai N Al-Qudah, Mohammad S Albsoul, Nader M |
| description | To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out. Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations. Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect. |
| doi_str_mv | 10.15537/smj.2017.10.20294 |
| format | Article |
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A randomized controlled study</title><source>MEDLINE</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Mismar, Ayman A ; Mahseeri, Mohammad I ; Al-Ghazawi, Mutasim A ; Obeidat, Firas W ; Albsoul, Mai N ; Al-Qudah, Mohammad S ; Albsoul, Nader M</creator><creatorcontrib>Mismar, Ayman A ; Mahseeri, Mohammad I ; Al-Ghazawi, Mutasim A ; Obeidat, Firas W ; Albsoul, Mai N ; Al-Qudah, Mohammad S ; Albsoul, Nader M</creatorcontrib><description>To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out. Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations. Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect.</description><identifier>ISSN: 0379-5284</identifier><identifier>EISSN: 1658-3175</identifier><identifier>DOI: 10.15537/smj.2017.10.20294</identifier><identifier>PMID: 28917062</identifier><language>eng</language><publisher>Saudi Arabia: Saudi Medical Journal</publisher><subject>Acetaminophen - therapeutic use ; Adult ; Analgesics, Non-Narcotic - therapeutic use ; Analgesics, Opioid - therapeutic use ; Anesthetics, Local - therapeutic use ; Bupivacaine ; Bupivacaine - therapeutic use ; Dosage and administration ; Double-Blind Method ; Drug Combinations ; Drug therapy ; Epinephrine - therapeutic use ; Female ; Humans ; Injections ; Jordan ; Male ; Meperidine - therapeutic use ; Middle Aged ; Morphine - therapeutic use ; Original ; Pain Management ; Pain Measurement ; Pain, Postoperative - prevention & control ; Postoperative pain ; Risk factors ; Surgical Wound ; Thyroidectomy ; Thyroidectomy - methods ; Tramadol - therapeutic use ; Treatment Outcome ; Vasoconstrictor Agents - therapeutic use</subject><ispartof>Saudi medical journal, 2017-10, Vol.38 (10), p.994-999</ispartof><rights>COPYRIGHT 2017 Saudi Medical Journal</rights><rights>Copyright: © Saudi Medical Journal 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694648/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694648/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28917062$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mismar, Ayman A</creatorcontrib><creatorcontrib>Mahseeri, Mohammad I</creatorcontrib><creatorcontrib>Al-Ghazawi, Mutasim A</creatorcontrib><creatorcontrib>Obeidat, Firas W</creatorcontrib><creatorcontrib>Albsoul, Mai N</creatorcontrib><creatorcontrib>Al-Qudah, Mohammad S</creatorcontrib><creatorcontrib>Albsoul, Nader M</creatorcontrib><title>Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study</title><title>Saudi medical journal</title><addtitle>Saudi Med J</addtitle><description>To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out. Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations. Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect.</description><subject>Acetaminophen - therapeutic use</subject><subject>Adult</subject><subject>Analgesics, Non-Narcotic - therapeutic use</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>Bupivacaine</subject><subject>Bupivacaine - therapeutic use</subject><subject>Dosage and administration</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Drug therapy</subject><subject>Epinephrine - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Injections</subject><subject>Jordan</subject><subject>Male</subject><subject>Meperidine - therapeutic use</subject><subject>Middle Aged</subject><subject>Morphine - therapeutic use</subject><subject>Original</subject><subject>Pain Management</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - prevention & control</subject><subject>Postoperative pain</subject><subject>Risk factors</subject><subject>Surgical Wound</subject><subject>Thyroidectomy</subject><subject>Thyroidectomy - methods</subject><subject>Tramadol - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Vasoconstrictor Agents - therapeutic use</subject><issn>0379-5284</issn><issn>1658-3175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptUtFqFDEUDWKxa_UHfJCACL7MmGSSycyLsBRthYIvio8hm9zppswka5JpWf_BfzazW0sLkocbzr3n5N6bg9AbSmoqRCM_pummZoTKuiCMsJ4_Qyvaiq5qqBTP0Yo0sq8E6_gpepnSDSFN25L2BTplXU8ladkK_fkZZm-x84Mbc9TZBY_vXN7izbxzt9po5wGTWrw_oiEeYpgz1jaC1-OStwES9iFjCyaCToB3hYf1kCHivN3H4Eomh2lf4zWO2tswud9gsQk-xzCO5ZrybPev0MmgxwSv7-MZ-vHl8_fzy-rq28XX8_VVZThhuRoGrhmVEmDgrOkFtZ0RRHBByIbawRjoLSsTUm3YIFkrZMd6zTRhYG1PeHOGPh11d_NmAmugtKFHtYtu0nGvgnbqaca7rboOt0q0PW95VwQ-3AvE8GuGlNXkkoFx1B7CnBTtOSGCyW55692x9FqPoMqiQ1E0S7laCyY44bRZBOv_VJVjYXJlTVD-B54S2JFgYkgpwvDQPSXqYA9V7KEWeyzIwR6F9Pbx3A-Uf35o_gJDtbjK</recordid><startdate>20171001</startdate><enddate>20171001</enddate><creator>Mismar, Ayman A</creator><creator>Mahseeri, Mohammad I</creator><creator>Al-Ghazawi, Mutasim A</creator><creator>Obeidat, Firas W</creator><creator>Albsoul, Mai N</creator><creator>Al-Qudah, Mohammad S</creator><creator>Albsoul, Nader M</creator><general>Saudi Medical Journal</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20171001</creationdate><title>Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study</title><author>Mismar, Ayman A ; Mahseeri, Mohammad I ; Al-Ghazawi, Mutasim A ; Obeidat, Firas W ; Albsoul, Mai N ; Al-Qudah, Mohammad S ; Albsoul, Nader M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-ff4a2177eef423951d8c5054500b1dfcce9d29171ac2f72657829a2a02edd9043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Acetaminophen - therapeutic use</topic><topic>Adult</topic><topic>Analgesics, Non-Narcotic - therapeutic use</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>Bupivacaine</topic><topic>Bupivacaine - therapeutic use</topic><topic>Dosage and administration</topic><topic>Double-Blind Method</topic><topic>Drug Combinations</topic><topic>Drug therapy</topic><topic>Epinephrine - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Injections</topic><topic>Jordan</topic><topic>Male</topic><topic>Meperidine - therapeutic use</topic><topic>Middle Aged</topic><topic>Morphine - therapeutic use</topic><topic>Original</topic><topic>Pain Management</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - prevention & control</topic><topic>Postoperative pain</topic><topic>Risk factors</topic><topic>Surgical Wound</topic><topic>Thyroidectomy</topic><topic>Thyroidectomy - methods</topic><topic>Tramadol - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Vasoconstrictor Agents - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mismar, Ayman A</creatorcontrib><creatorcontrib>Mahseeri, Mohammad I</creatorcontrib><creatorcontrib>Al-Ghazawi, Mutasim A</creatorcontrib><creatorcontrib>Obeidat, Firas W</creatorcontrib><creatorcontrib>Albsoul, Mai N</creatorcontrib><creatorcontrib>Al-Qudah, Mohammad S</creatorcontrib><creatorcontrib>Albsoul, Nader M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Saudi medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mismar, Ayman A</au><au>Mahseeri, Mohammad I</au><au>Al-Ghazawi, Mutasim A</au><au>Obeidat, Firas W</au><au>Albsoul, Mai N</au><au>Al-Qudah, Mohammad S</au><au>Albsoul, Nader M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study</atitle><jtitle>Saudi medical journal</jtitle><addtitle>Saudi Med J</addtitle><date>2017-10-01</date><risdate>2017</risdate><volume>38</volume><issue>10</issue><spage>994</spage><epage>999</epage><pages>994-999</pages><issn>0379-5284</issn><eissn>1658-3175</eissn><abstract>To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out. Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations. Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect.</abstract><cop>Saudi Arabia</cop><pub>Saudi Medical Journal</pub><pmid>28917062</pmid><doi>10.15537/smj.2017.10.20294</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acetaminophen - therapeutic use Adult Analgesics, Non-Narcotic - therapeutic use Analgesics, Opioid - therapeutic use Anesthetics, Local - therapeutic use Bupivacaine Bupivacaine - therapeutic use Dosage and administration Double-Blind Method Drug Combinations Drug therapy Epinephrine - therapeutic use Female Humans Injections Jordan Male Meperidine - therapeutic use Middle Aged Morphine - therapeutic use Original Pain Management Pain Measurement Pain, Postoperative - prevention & control Postoperative pain Risk factors Surgical Wound Thyroidectomy Thyroidectomy - methods Tramadol - therapeutic use Treatment Outcome Vasoconstrictor Agents - therapeutic use |
| title | Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study |
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