Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release

In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body’s serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse pri...

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Veröffentlicht in:	Scientific reports 2017-11, Vol.7 (1), p.1-12, Article 15650
Hauptverfasser:	Strege, Peter R., Knutson, Kaitlyn, Eggers, Samuel J., Li, Joyce H., Wang, Fan, Linden, David, Szurszewski, Joseph H., Milescu, Lorin, Leiter, Andrew B., Farrugia, Gianrico, Beyder, Arthur
Format:	Artikel
Sprache:	eng
Schlagworte:	13/31 13/51 38/77 64/110 64/60 692/4020/2741 692/4020/2741/520/1584 9/74 Electrophysiology Epithelium Excitability Humanities and Social Sciences Molecular modelling multidisciplinary Science Science (multidisciplinary) Serotonin Sodium Sodium channels (voltage-gated)
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