Effects of β-estradiol on cold-sensitive receptor channel TRPM8 in ovariectomized rats

Transient receptor potential cation channel subfamily M member 8 (TRPM8) is associated with sensitivity to cold sensation in mammals. A previous study demonstrated that TRPM8 was overexpressed in the skin of ovariectomized (OVX) rats due to the loss of estrogen. In the present study, we investigated...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental Animals 2017, Vol.66(4), pp.337-343
Hauptverfasser:	Kubo, Takuro, Tsuji, Shunichiro, Amano, Tsukuru, Yoshino, Fumi, Niwa, Yoko, Kasahara, Kyoko, Yoshida, Saori, Mukaisho, Ken-ichi, Sugihara, Hiroyuki, Tanaka, Sachiko, Kimura, Fuminori, Takahashi, Kentaro, Murakami, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cold Temperature cold-sensitive TRPM8 channel receptor Estradiol - administration & dosage Estradiol - pharmacology estrogen estrogen replacement Estrogen Replacement Therapy Female Gene Expression - drug effects Original Ovariectomy oversensitivity to cold post-menopause Postmenopause - physiology Rats, Sprague-Dawley RNA, Messenger - genetics RNA, Messenger - metabolism Sensation - genetics Sensation - physiology Skin - metabolism TRPM Cation Channels - genetics TRPM Cation Channels - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!