Interleukin‐27 signalling induces stem cell antigen‐1 expression in T lymphocytes in vivo

Summary Stem cell antigen‐1 (Sca‐1/Ly6A/E) is a cell surface glycoprotein that is often used as a biomarker for stem cells and cell stemness. However, it is not clear what factors can directly induce the expression of Sca‐1/Ly6A/E in T lymphocytes in vivo, and if induction of Sca‐1 is associated wit...

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Veröffentlicht in:	Immunology 2017-12, Vol.152 (4), p.638-647
Hauptverfasser:	Liu, Zhihao, Wu, Lisha, Zhu, Jing, Zhu, Xiaotong, Zhu, Jianmin, Liu, Jin‐Qing, Zhang, Jianchao, Davis, Jonathan P., Varikuti, Sanjay, Satoskar, Abhay R., Zhou, Jie, Li, Ming‐Song, Bai, Xue‐Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - genetics Antigens, CD - immunology Antigens, Ly - genetics Antigens, Ly - immunology Gene Expression Regulation - immunology Immunologic Memory Interleukins - genetics Interleukins - immunology interleukin‐27 Membrane Proteins - genetics Membrane Proteins - immunology Mice Mice, Knockout Original Receptors, Cytokine - genetics Receptors, Cytokine - immunology Signal Transduction - genetics Signal Transduction - immunology stem cell antigen‐1 T-Lymphocytes - immunology T‐cell memory
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