Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination

The alkynylation of naphthols takes place with total regiocontrol at the peri position of the hydroxyl group in the presence of [RuCl2(p-cymene)]2 as the catalyst. This reaction features high functional group tolerance. The related ortho-alkynylation of benzoic acids proceeds under similar condition...

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Veröffentlicht in:	Organic letters 2017-10, Vol.19 (20), p.5561-5564
Hauptverfasser:	Tan, Eric, Konovalov, Andrey I, Fernández, Gabriela A, Dorel, Ruth, Echavarren, Antonio M
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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