The Landscape of Type VI Secretion across Human Gut Microbiomes Reveals Its Role in Community Composition

Although gut microbiome composition is well defined, the mechanisms underlying community assembly remain poorly understood. Bacteroidales possess three genetic architectures (GA1–3) of the type VI secretion system (T6SS), an effector delivery pathway that mediates interbacterial competition. Here we...

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Veröffentlicht in:	Cell host & microbe 2017-09, Vol.22 (3), p.411-419.e4
Hauptverfasser:	Verster, Adrian J., Ross, Benjamin D., Radey, Matthew C., Bao, Yiqiao, Goodman, Andrew L., Mougous, Joseph D., Borenstein, Elhanan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Bacteria - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteroidales Bacteroides - classification Bacteroides - genetics Bacteroides - isolation & purification Bacteroides - metabolism Biodiversity Female Gastrointestinal Microbiome Gastrointestinal Tract - microbiology human microbiome Humans infant microbiome interbacterial competition Male metagenomics microbiome assembly Middle Aged Phylogeny T6SS toxin type VI secretion system Type VI Secretion Systems - genetics Type VI Secretion Systems - metabolism Young Adult
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