Across the tree of life, radiation resistance is governed by antioxidant Mn2+, gauged by paramagnetic resonance

Despite concerted functional genomic efforts to understand the complex phenotype of ionizing radiation (IR) resistance, a genome sequence cannot predict whether a cell is IR-resistant or not. Instead, we report that absorption-display electron paramagnetic resonance (EPR) spectroscopy of nonirradiat...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2017-10, Vol.114 (44), p.E9253-E9260
Hauptverfasser:	Sharma, Ajay, Gaidamakova, Elena K., Grichenko, Olga, Matrosova, Vera Y., Hoeke, Veronika, Klimenkova, Polina, Conze, Isabel H., Volpe, Robert P., Tkavc, Rok, Gostinčar, Cene, Gunde-Cimerman, Nina, DiRuggiero, Jocelyne, Shuryak, Igor, Ozarowski, Andrew, Hoffman, Brian M., Daly, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Archaea Bacteria Biological Sciences Cell size Chelation Deoxyribonucleic acid Diagnostic systems DNA DNA damage DNA repair Electron paramagnetic resonance Enzymes Eukaryotes Fungi Gamma rays Genomes I.R. radiation Infrared radiation Ionizing radiation Manganese ions Metabolites Nucleotide sequence Nutritional status Orthophosphate Peptides Physical Sciences PNAS Plus Radiation Radiation tolerance Radioresistance Resonance Spectroscopy Splitting Superoxide dismutase Survival Symmetry γ Radiation
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