Cytomegaloviral hypophysitis in a simian immunodeficiency virus‐infected rhesus macaque (Macacca mulatta)
Rhesus macaques experimentally infected with Simian Immunodeficiency Virus (SIV) experience immunosuppression and often opportunistic infection. Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low‐level replica...
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| Veröffentlicht in: | Journal of medical primatology 2017-12, Vol.46 (6), p.364-367 |
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| container_end_page | 367 |
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| container_issue | 6 |
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| container_title | Journal of medical primatology |
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| creator | Berg, Melissa R. Owston, Michael A. Gauduin, Marie‐Claire Assaf, Basel T. Lewis, Anne D. Dick, Edward J. |
| description | Rhesus macaques experimentally infected with Simian Immunodeficiency Virus (SIV) experience immunosuppression and often opportunistic infection. Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low‐level replication in immunocompetent monkeys. Upon SIV‐mediated immunodeficiency, RhCMV reactivates and results in lesions in numerous organ systems including the nervous and reproductive systems. We report the first case of cytomegaloviral hypophysitis in a SIV‐immunocompromised rhesus macaque. |
| doi_str_mv | 10.1111/jmp.12289 |
| format | Article |
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Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low‐level replication in immunocompetent monkeys. Upon SIV‐mediated immunodeficiency, RhCMV reactivates and results in lesions in numerous organ systems including the nervous and reproductive systems. 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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Animals Cytomegalovirus Cytomegalovirus - isolation & purification Female Hypophysitis - complications Hypophysitis - immunology Hypophysitis - virology Immunocompromised Host Immunosuppression inclusions intranuclear intra‐cytoplasmic Macaca mulatta Monkeys & apes non‐human primate Opportunist infection Opportunistic Infections - complications Opportunistic Infections - immunology Opportunistic Infections - virology pituitary Primates Simian Acquired Immunodeficiency Syndrome - complications Simian Immunodeficiency Virus - physiology viral |
| title | Cytomegaloviral hypophysitis in a simian immunodeficiency virus‐infected rhesus macaque (Macacca mulatta) |
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