Effects of ursolic and oleanolic on SK-MEL-2 melanoma cells: In vitro and in vivo assays

Among the triterpenoids, oleanolic acid (OA) and its isomer, ursolic acid (UA) are promising therapeutic candidates, with potential benefits in the management of melanoma. In this study, we aimed to examine the in vitro and in vivo anti-invasive and anti-metastatic activity of OA and UA to determine...

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Veröffentlicht in:	International journal of oncology 2017-12, Vol.51 (6), p.1651-1660
Hauptverfasser:	Caunii, Angela, Oprean, Camelia, Cristea, Mirabela, Ivan, Alexandra, Danciu, Corina, Tatu, Calin, Paunescu, Virgil, Marti, Daniela, Tzanakakis, George, Spandidos, Demetrios A, Tsatsakis, Aristides, Susan, Razvan, Soica, Codruta, Avram, Stefana, Dehelean, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - pharmacology Animals anti-angiogenic anti-invasive Care and treatment Cell Adhesion - drug effects Cell Cycle - drug effects Cell Line, Tumor Cell Proliferation - drug effects Chick Embryo Chorioallantoic Membrane - blood supply Chorioallantoic Membrane - drug effects Development and progression Health aspects Humans Kinases Melanoma Melanoma - blood supply Melanoma - drug therapy Melanoma - pathology Mutation Neovascularization, Physiologic - drug effects oleanolic acid Oleanolic Acid - pharmacology Skin cancer Skin Neoplasms - blood supply Skin Neoplasms - drug therapy Skin Neoplasms - pathology Studies Terpenoids Triterpenes - pharmacology Ursolic Acid
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