Building the foundation for genomics in precision medicine

Precision medicine has the potential to profoundly improve the practice of medicine. However, the advances required will take time to implement. Genetics is already being used to direct clinical decision-making and its contribution is likely to increase. To accelerate these advances, fundamental cha...

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Veröffentlicht in:Nature (London) 2015-10, Vol.526 (7573), p.336-342
Hauptverfasser: Aronson, Samuel J., Rehm, Heidi L.
Format: Artikel
Sprache:eng
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Zusammenfassung:Precision medicine has the potential to profoundly improve the practice of medicine. However, the advances required will take time to implement. Genetics is already being used to direct clinical decision-making and its contribution is likely to increase. To accelerate these advances, fundamental changes are needed in the infrastructure and mechanisms for data collection, storage and sharing. This will create a continuously learning health-care system with seamless cycling between clinical care and research. Patients must be educated about the benefits of sharing data. The building blocks for such a system are already forming and they will accelerate the adoption of precision medicine.
ISSN:0028-0836
1476-4687
DOI:10.1038/nature15816