The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology

Mobile element insertions (MEIs) represent ∼25% of all structural variants in human genomes. Moreover, when they disrupt genes, MEIs can influence human traits and diseases. Therefore, MEIs should be fully discovered along with other forms of genetic variation in whole genome sequencing (WGS) projec...

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Veröffentlicht in:	Genome research 2017-11, Vol.27 (11), p.1916-1929
Hauptverfasser:	Gardner, Eugene J, Lam, Vincent K, Harris, Daniel N, Chuang, Nelson T, Scott, Emma C, Pittard, W Stephen, Mills, Ryan E, Devine, Scott E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Computational Biology - methods Databases, Genetic DNA Transposable Elements Evolution, Molecular High-Throughput Nucleotide Sequencing - methods Humans Method Neanderthals - genetics Pan troglodytes - genetics Polymorphism, Single Nucleotide Software Whole Genome Sequencing - methods
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