Covalent bonding of heme to protein prevents heme capture by nontypeable Haemophilus influenzae

Nontypeable Haemophilus influenzae (NTHi) are Gram‐negative pathogens that contribute to a variety of diseases, including acute otitis media and chronic obstructive pulmonary disease. As NTHi have an absolute requirement for heme during aerobic growth, these bacteria have to scavenge heme from their...

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Veröffentlicht in:	FEBS open bio 2017-11, Vol.7 (11), p.1778-1783
Hauptverfasser:	Sgheiza, Valerie, Novick, Bethany, Stanton, Sarah, Pierce, Jeanetta, Kalmeta, Breanne, Holmquist, Melody Frink, Grimaldi, Kyle, Bren, Kara L., Michel, Lea Vacca
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic obstructive pulmonary disease Cytochrome cytochrome c Donations E coli Ear diseases Haemophilus influenzae Heme Hemoglobin Lung diseases Mutagenesis Obstructive lung disease Otitis media Peptides Proteins
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