FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs

Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature degeneration and calcification of intervertebral discs. Independent genome-wide association analyses for skeletal dysplasia (short limbs) within a single breed (P Bonferroni = 0.01) and intervertebral disc disease...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2017-10, Vol.114 (43), p.11476-11481
Hauptverfasser:	Brown, Emily A., Dickinson, Peter J., Mansour, Tamer, Sturges, Beverly K., Aguilar, Miriam, Young, Amy E., Korff, Courtney, Lind, Jenna, Ettinger, Cassandra L., Varon, Samuel, Pollard, Rachel, Brown, C. Titus, Raudsepp, Terje, Bannasch, Danika L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Biological Sciences Bone dysplasia Bones Breeding of animals Calcification Chondrodystrophy Degeneration Dogs Fibroblast growth factor 4 Gene sequencing Genetics Genomes Intervertebral discs Long bone Signaling Skeleton
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!