Rhinacanthin C Alleviates Amyloid-β Fibrils’ Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid-β, and Interferon-γ in Glial Cells

Neuroinflammation plays a central role in the pathophysiology of Alzheimer’s disease (AD). Compounds that suppress neuroinflammation have been identified as potential therapeutic targets for AD. Rhinacanthin C (RC), a naphthoquinone ester found in Rhinacanthus nasutus Kurz (Acanthaceae), is currentl...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2017-01, Vol.2017 (2017), p.1-18
Hauptverfasser:	Wen, Shu-Fang, Perng, Ming-Der, Pan, I-Horng, Lu, I-Huang, Chang, Chih-Hsuan, Lin, Ni-Hsuan, Li, Ming-Han, Chuang, Kai-An, Takahashi, Tomoya
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apoptosis Brain research Kinases Neurons Neurosciences Penicillin R&D Research & development Rodents Toxicity Tuberculosis Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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