MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication
Treslin, which is essential for incorporation of Cdc45 into the replicative helicase, possesses a partner called MTBP (Mdm2-binding protein). We have analyzed and human MTBP to assess its role in DNA replication. Depletion of MTBP from egg extracts, which also removes Treslin, abolishes DNA replicat...
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| Veröffentlicht in: | Molecular biology of the cell 2017-11, Vol.28 (22), p.2998-3012 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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