Human Cytomegalovirus Particles Treated with Specific Antibodies Induce Intrinsic and Adaptive but Not Innate Immune Responses

Human cytomegalovirus (HCMV) persistently infects 40% to 100% of the human population worldwide. Experimental and clinical evidence indicates that humoral immunity to HCMV plays an important role in restricting virus dissemination and protecting the infected host from disease. Specific immunoglobuli...

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Veröffentlicht in:	Journal of virology 2017-11, Vol.91 (22)
Hauptverfasser:	Wu, Zeguang, Qin, Ruifang, Wang, Li, Bosso, Matteo, Scherer, Myriam, Stamminger, Thomas, Hotter, Dominik, Mertens, Thomas, Frascaroli, Giada
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral - immunology CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - pathology CD4-Positive T-Lymphocytes - virology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - pathology CD8-Positive T-Lymphocytes - virology Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Cytomegalovirus Infections - pathology Female Humans Immunity, Cellular Immunity, Innate Macrophages - immunology Macrophages - pathology Macrophages - virology Male Pathogenesis and Immunity
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