HLA-B14:02-Restricted Env-Specific CD8 + T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

Immune control of human immunodeficiency virus type 1 (HIV) infection is typically associated with effective Gag-specific CD8 T-cell responses. We here focus on HLA-B*14, which protects against HIV disease progression, but the immunodominant HLA-B*14-restricted anti-HIV response is Env specific (ERY...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of virology 2017-11, Vol.91 (22), p.e00544-17
Hauptverfasser:	Leitman, Ellen M, Willberg, Christian B, Tsai, Ming-Han, Chen, Huabiao, Buus, Søren, Chen, Fabian, Riddell, Lynn, Haas, David, Fellay, Jacques, Goedert, James J, Piechocka-Trocha, Alicja, Walker, Bruce D, Martin, Jeffrey, Deeks, Steven, Wolinsky, Steven M, Martinson, Jeremy, Martin, Maureen, Qi, Ying, Sáez-Cirión, Asier, Yang, Otto O, Matthews, Philippa C, Carrington, Mary, Goulder, Philip J R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult CD8-Positive T-Lymphocytes gag Gene Products, Human Immunodeficiency Virus gag Gene Products, Human Immunodeficiency Virus - immunology HIV Envelope Protein gp160 HIV Envelope Protein gp160 - immunology HIV Infections HIV Infections - immunology HIV Infections - pathology HIV Infections - therapy HIV-1 HIV-1 - immunology HLA-B14 Antigen HLA-B14 Antigen - immunology Humans Immunity, Cellular Immunology Life Sciences Pathogenesis and Immunity Peptides Peptides - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!