Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol
Survival outcomes are related to treatment choices in a line of therapy and to treatment sequences across all lines of therapy. The Real-World Treatment Sequences and Outcomes among Patients with NSCLC (RESOUNDS) study is designed to (1) evaluate treatment sequences used for patients who receive at...
Gespeichert in:
| Veröffentlicht in: | JMIR research protocols 2017-10, Vol.6 (10), p.e195-e195 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e195 |
|---|---|
| container_issue | 10 |
| container_start_page | e195 |
| container_title | JMIR research protocols |
| container_volume | 6 |
| creator | Hess, Lisa M Kern, David M Carter, Gebra Cuyun Winfree, Katherine Wang, Liya Sontag, Angelina Oton, Ana B |
| description | Survival outcomes are related to treatment choices in a line of therapy and to treatment sequences across all lines of therapy.
The Real-World Treatment Sequences and Outcomes among Patients with NSCLC (RESOUNDS) study is designed to (1) evaluate treatment sequences used for patients who receive at least two lines of therapy for non-small cell lung cancer (NSCLC) in the United States and (2) evaluate patient outcomes in terms of progression-free and overall survival related to treatment sequencing. Additional objectives include the evaluation of symptoms, comorbidities, and health care resource utilization and costs.
Patients will be censored at loss to follow-up due to leaving the health plan or reaching the end of the study period.
This study is ongoing.
The RESOUNDS cohort study is a novel approach to building a comprehensive dataset that mimics a prospective observational study using linked patient-level data from four real-world data sources. This study will provide timely information on the sequencing of treatments for patients with NSCLC. |
| doi_str_mv | 10.2196/resprot.7750 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5658639</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2509007703</sourcerecordid><originalsourceid>FETCH-LOGICAL-c374t-c67343d2679e8dce9d354ac7ec354585bc42e956f186f7d1ed668ea1f1f446e3</originalsourceid><addsrcrecordid>eNpdkc9rHCEcxaW0NCHNreci9JJCJ1Vn1LGHQNimP2DJhsyGHMXod7ITZnSrTiH_Qv_qGrINaT34FD8-fD6E3lJyzKgSnyKkbQz5WEpOXqB9qpiqiGzal8_We-gwpTtSRiulYuI12mOKMEqZ2ke_L8GM1XWIo8PrCCZP4DPu4OcM3kLCxju8mrMNU9mcTsHf4guThwIlfD3kDT4PvuomM454AWVazoVYmHI34qPLs251df6l-4AHj_MG8JUfMjjcZZMhfS46u3t8UQIEG8Y36FVvxgSHOz1A669n68X3arn69mNxuqxsLZtcWSHrpnZMSAWts6BczRtjJdiivOU3tmGguOhpK3rpKDghWjC0p33TCKgP0Mmj7Xa-maAY-BzNqLdxmEy818EM-t8TP2z0bfilueCtqFUxONoZxFC-KWU9DcmW8MZDmJOmipOGFpoW9P1_6F2Yoy_pNONEESIlqQv18ZGyMaQUoX96DCX6oWa9q1k_1Fzwd88DPMF_S63_AK7kpWc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2509007703</pqid></control><display><type>article</type><title>Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Hess, Lisa M ; Kern, David M ; Carter, Gebra Cuyun ; Winfree, Katherine ; Wang, Liya ; Sontag, Angelina ; Oton, Ana B</creator><creatorcontrib>Hess, Lisa M ; Kern, David M ; Carter, Gebra Cuyun ; Winfree, Katherine ; Wang, Liya ; Sontag, Angelina ; Oton, Ana B</creatorcontrib><description>Survival outcomes are related to treatment choices in a line of therapy and to treatment sequences across all lines of therapy.
The Real-World Treatment Sequences and Outcomes among Patients with NSCLC (RESOUNDS) study is designed to (1) evaluate treatment sequences used for patients who receive at least two lines of therapy for non-small cell lung cancer (NSCLC) in the United States and (2) evaluate patient outcomes in terms of progression-free and overall survival related to treatment sequencing. Additional objectives include the evaluation of symptoms, comorbidities, and health care resource utilization and costs.
Patients will be censored at loss to follow-up due to leaving the health plan or reaching the end of the study period.
This study is ongoing.
The RESOUNDS cohort study is a novel approach to building a comprehensive dataset that mimics a prospective observational study using linked patient-level data from four real-world data sources. This study will provide timely information on the sequencing of treatments for patients with NSCLC.</description><identifier>ISSN: 1929-0748</identifier><identifier>EISSN: 1929-0748</identifier><identifier>DOI: 10.2196/resprot.7750</identifier><identifier>PMID: 29021129</identifier><language>eng</language><publisher>Canada: JMIR Publications</publisher><subject>Cancer therapies ; Chemotherapy ; FDA approval ; Health care ; Lung cancer ; Medical records ; Mortality ; Oncology ; Patients ; Pharmacy ; Physicians ; Population ; Protocol</subject><ispartof>JMIR research protocols, 2017-10, Vol.6 (10), p.e195-e195</ispartof><rights>2017. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Lisa M Hess, David M Kern, Gebra Cuyun Carter, Katherine Winfree, Liya Wang, Angelina Sontag, Ana B Oton. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 11.10.2017. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-c67343d2679e8dce9d354ac7ec354585bc42e956f186f7d1ed668ea1f1f446e3</citedby><cites>FETCH-LOGICAL-c374t-c67343d2679e8dce9d354ac7ec354585bc42e956f186f7d1ed668ea1f1f446e3</cites><orcidid>0000-0001-5417-3925 ; 0000-0003-2088-1004 ; 0000-0002-6126-7353 ; 0000-0003-3631-3941 ; 0000-0003-0317-5685 ; 0000-0003-4012-4537 ; 0000-0002-6549-0069</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658639/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658639/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29021129$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hess, Lisa M</creatorcontrib><creatorcontrib>Kern, David M</creatorcontrib><creatorcontrib>Carter, Gebra Cuyun</creatorcontrib><creatorcontrib>Winfree, Katherine</creatorcontrib><creatorcontrib>Wang, Liya</creatorcontrib><creatorcontrib>Sontag, Angelina</creatorcontrib><creatorcontrib>Oton, Ana B</creatorcontrib><title>Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol</title><title>JMIR research protocols</title><addtitle>JMIR Res Protoc</addtitle><description>Survival outcomes are related to treatment choices in a line of therapy and to treatment sequences across all lines of therapy.
The Real-World Treatment Sequences and Outcomes among Patients with NSCLC (RESOUNDS) study is designed to (1) evaluate treatment sequences used for patients who receive at least two lines of therapy for non-small cell lung cancer (NSCLC) in the United States and (2) evaluate patient outcomes in terms of progression-free and overall survival related to treatment sequencing. Additional objectives include the evaluation of symptoms, comorbidities, and health care resource utilization and costs.
Patients will be censored at loss to follow-up due to leaving the health plan or reaching the end of the study period.
This study is ongoing.
The RESOUNDS cohort study is a novel approach to building a comprehensive dataset that mimics a prospective observational study using linked patient-level data from four real-world data sources. This study will provide timely information on the sequencing of treatments for patients with NSCLC.</description><subject>Cancer therapies</subject><subject>Chemotherapy</subject><subject>FDA approval</subject><subject>Health care</subject><subject>Lung cancer</subject><subject>Medical records</subject><subject>Mortality</subject><subject>Oncology</subject><subject>Patients</subject><subject>Pharmacy</subject><subject>Physicians</subject><subject>Population</subject><subject>Protocol</subject><issn>1929-0748</issn><issn>1929-0748</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc9rHCEcxaW0NCHNreci9JJCJ1Vn1LGHQNimP2DJhsyGHMXod7ITZnSrTiH_Qv_qGrINaT34FD8-fD6E3lJyzKgSnyKkbQz5WEpOXqB9qpiqiGzal8_We-gwpTtSRiulYuI12mOKMEqZ2ke_L8GM1XWIo8PrCCZP4DPu4OcM3kLCxju8mrMNU9mcTsHf4guThwIlfD3kDT4PvuomM454AWVazoVYmHI34qPLs251df6l-4AHj_MG8JUfMjjcZZMhfS46u3t8UQIEG8Y36FVvxgSHOz1A669n68X3arn69mNxuqxsLZtcWSHrpnZMSAWts6BczRtjJdiivOU3tmGguOhpK3rpKDghWjC0p33TCKgP0Mmj7Xa-maAY-BzNqLdxmEy818EM-t8TP2z0bfilueCtqFUxONoZxFC-KWU9DcmW8MZDmJOmipOGFpoW9P1_6F2Yoy_pNONEESIlqQv18ZGyMaQUoX96DCX6oWa9q1k_1Fzwd88DPMF_S63_AK7kpWc</recordid><startdate>20171011</startdate><enddate>20171011</enddate><creator>Hess, Lisa M</creator><creator>Kern, David M</creator><creator>Carter, Gebra Cuyun</creator><creator>Winfree, Katherine</creator><creator>Wang, Liya</creator><creator>Sontag, Angelina</creator><creator>Oton, Ana B</creator><general>JMIR Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5417-3925</orcidid><orcidid>https://orcid.org/0000-0003-2088-1004</orcidid><orcidid>https://orcid.org/0000-0002-6126-7353</orcidid><orcidid>https://orcid.org/0000-0003-3631-3941</orcidid><orcidid>https://orcid.org/0000-0003-0317-5685</orcidid><orcidid>https://orcid.org/0000-0003-4012-4537</orcidid><orcidid>https://orcid.org/0000-0002-6549-0069</orcidid></search><sort><creationdate>20171011</creationdate><title>Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol</title><author>Hess, Lisa M ; Kern, David M ; Carter, Gebra Cuyun ; Winfree, Katherine ; Wang, Liya ; Sontag, Angelina ; Oton, Ana B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-c67343d2679e8dce9d354ac7ec354585bc42e956f186f7d1ed668ea1f1f446e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Cancer therapies</topic><topic>Chemotherapy</topic><topic>FDA approval</topic><topic>Health care</topic><topic>Lung cancer</topic><topic>Medical records</topic><topic>Mortality</topic><topic>Oncology</topic><topic>Patients</topic><topic>Pharmacy</topic><topic>Physicians</topic><topic>Population</topic><topic>Protocol</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hess, Lisa M</creatorcontrib><creatorcontrib>Kern, David M</creatorcontrib><creatorcontrib>Carter, Gebra Cuyun</creatorcontrib><creatorcontrib>Winfree, Katherine</creatorcontrib><creatorcontrib>Wang, Liya</creatorcontrib><creatorcontrib>Sontag, Angelina</creatorcontrib><creatorcontrib>Oton, Ana B</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>JMIR research protocols</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hess, Lisa M</au><au>Kern, David M</au><au>Carter, Gebra Cuyun</au><au>Winfree, Katherine</au><au>Wang, Liya</au><au>Sontag, Angelina</au><au>Oton, Ana B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol</atitle><jtitle>JMIR research protocols</jtitle><addtitle>JMIR Res Protoc</addtitle><date>2017-10-11</date><risdate>2017</risdate><volume>6</volume><issue>10</issue><spage>e195</spage><epage>e195</epage><pages>e195-e195</pages><issn>1929-0748</issn><eissn>1929-0748</eissn><abstract>Survival outcomes are related to treatment choices in a line of therapy and to treatment sequences across all lines of therapy.
The Real-World Treatment Sequences and Outcomes among Patients with NSCLC (RESOUNDS) study is designed to (1) evaluate treatment sequences used for patients who receive at least two lines of therapy for non-small cell lung cancer (NSCLC) in the United States and (2) evaluate patient outcomes in terms of progression-free and overall survival related to treatment sequencing. Additional objectives include the evaluation of symptoms, comorbidities, and health care resource utilization and costs.
Patients will be censored at loss to follow-up due to leaving the health plan or reaching the end of the study period.
This study is ongoing.
The RESOUNDS cohort study is a novel approach to building a comprehensive dataset that mimics a prospective observational study using linked patient-level data from four real-world data sources. This study will provide timely information on the sequencing of treatments for patients with NSCLC.</abstract><cop>Canada</cop><pub>JMIR Publications</pub><pmid>29021129</pmid><doi>10.2196/resprot.7750</doi><orcidid>https://orcid.org/0000-0001-5417-3925</orcidid><orcidid>https://orcid.org/0000-0003-2088-1004</orcidid><orcidid>https://orcid.org/0000-0002-6126-7353</orcidid><orcidid>https://orcid.org/0000-0003-3631-3941</orcidid><orcidid>https://orcid.org/0000-0003-0317-5685</orcidid><orcidid>https://orcid.org/0000-0003-4012-4537</orcidid><orcidid>https://orcid.org/0000-0002-6549-0069</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1929-0748 |
| ispartof | JMIR research protocols, 2017-10, Vol.6 (10), p.e195-e195 |
| issn | 1929-0748 1929-0748 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5658639 |
| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Cancer therapies Chemotherapy FDA approval Health care Lung cancer Medical records Mortality Oncology Patients Pharmacy Physicians Population Protocol |
| title | Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T11%3A34%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Real-World%20Treatment%20Sequences%20and%20Outcomes%20Among%20Patients%20With%20Non-Small%20Cell%20Lung%20Cancer%20(RESOUNDS)%20in%20the%20United%20States:%20Study%20Protocol&rft.jtitle=JMIR%20research%20protocols&rft.au=Hess,%20Lisa%20M&rft.date=2017-10-11&rft.volume=6&rft.issue=10&rft.spage=e195&rft.epage=e195&rft.pages=e195-e195&rft.issn=1929-0748&rft.eissn=1929-0748&rft_id=info:doi/10.2196/resprot.7750&rft_dat=%3Cproquest_pubme%3E2509007703%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2509007703&rft_id=info:pmid/29021129&rfr_iscdi=true |