Visible‐Light‐Mediated Selective Arylation of Cysteine in Batch and Flow

A mild visible‐light‐mediated strategy for cysteine arylation is presented. The method relies on the use of eosin Y as a metal‐free photocatalyst and aryldiazonium salts as arylating agents. The reaction can be significantly accelerated in a microflow reactor, whilst allowing the in situ formation o...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-10, Vol.56 (41), p.12702-12707
Hauptverfasser:	Bottecchia, Cecilia, Rubens, Maarten, Gunnoo, Smita B., Hessel, Volker, Madder, Annemieke, Noël, Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Buffers Communication Communications Cysteine cysteine arylation diazonium salts microreactors Phosphates photochemistry photoredox catalysis Reaction time Salts Yttrium
Online-Zugang:	Volltext
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