Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells

Pancreatic cancer stem cells (CSCs) play a crucial role in tumorigenesis and chemoresistance of pancreatic ductal adenocarcinoma. Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel secretory protein, has been shown to contribute to cancer progression and metastasis. Because the clinical r...

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Veröffentlicht in:Oncotarget 2017-09, Vol.8 (44), p.76398-76407
Hauptverfasser: Cho, Jae Hee, Kim, Sun A, Park, Soo Been, Kim, Hee Man, Song, Si Young
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Sprache:eng
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