Silencing PPA1 inhibits human epithelial ovarian cancer metastasis by suppressing the Wnt/β-catenin signaling pathway

Inorganic pyrophosphatase (PPA1) activity is a key determinant of cellular inorganic pyrophosphate levels, and its expression is correlated with growth of several solid tumors. To investigate this relationship, we first examined PPA1 expression in human epithelial ovarian cancer (EOC) samples, and f...

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Veröffentlicht in:Oncotarget 2017-09, Vol.8 (44), p.76266-76278
Hauptverfasser: Niu, Haiying, Zhou, Wei, Xu, Yingxi, Yin, Zhiqi, Shen, Wenzhi, Ye, Zhen, Liu, Yanhua, Chen, Yanan, Yang, Shuang, Xiang, Rong, Wang, Lina, Qu, Pengpeng
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Sprache:eng
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