Isolated left ventricular non-compaction (LVNC) and recurrent strokes: to anticoagulate or not to anticoagulate, that is the question
Isolated left ventricular non-compaction (LVNC) is an uncommon primary cardiomyopathy associated with significant risk of thromboembolic stroke. We report a case of a 69-year-old man with a medical history of ischaemic stroke who presented with a stroke for the second time, and during stroke workup...
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| creator | Subahi, Ahmed Hassan, Abubaker A I Abubakar, Hossam Ibrahim, Walid |
| description | Isolated left ventricular non-compaction (LVNC) is an uncommon primary cardiomyopathy associated with significant risk of thromboembolic stroke. We report a case of a 69-year-old man with a medical history of ischaemic stroke who presented with a stroke for the second time, and during stroke workup transthoracic echo was suggestive of increased apical trabeculation. He underwent cardiac MRI study to evaluate the left ventricular structure, which revealed LVNC cardiomyopathy, which we believe is the main culprit of his recurrent strokes. Given the high risk of stroke recurrence, antiplatelets followed by anticoagulation for secondary prevention were initiated. This case demonstrates the association between LVNC and recurrent stroke, with a literature review trying to address the dilemma facing the clinician to decide on anticoagulation in such patients. |
| doi_str_mv | 10.1136/bcr-2017-220954 |
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We report a case of a 69-year-old man with a medical history of ischaemic stroke who presented with a stroke for the second time, and during stroke workup transthoracic echo was suggestive of increased apical trabeculation. He underwent cardiac MRI study to evaluate the left ventricular structure, which revealed LVNC cardiomyopathy, which we believe is the main culprit of his recurrent strokes. Given the high risk of stroke recurrence, antiplatelets followed by anticoagulation for secondary prevention were initiated. 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| subjects | Aged Anticoagulants - administration & dosage Anticoagulants - therapeutic use Aspirin - administration & dosage Aspirin - therapeutic use Black Cardiac arrhythmia Cardiology Cardiomyopathy Case reports Diagnosis, Differential Family medical history Heart failure Humans Isolated Noncompaction of the Ventricular Myocardium - diagnosis Isolated Noncompaction of the Ventricular Myocardium - diagnostic imaging Isolated Noncompaction of the Ventricular Myocardium - drug therapy Magnetic Resonance Imaging Male NMR Nuclear magnetic resonance Patients Rare Disease Recurrence Stroke Stroke - etiology Thromboembolism Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Ticlopidine - therapeutic use USA/Canada |
| title | Isolated left ventricular non-compaction (LVNC) and recurrent strokes: to anticoagulate or not to anticoagulate, that is the question |
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