Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder

Background: Posttraumatic stress disorder (PTSD) is a severe problem among soldiers with combating experience difficult to treat. The pathogenesis is still not fully understood at the psychological level. Therefore, genetic research became a focus of interest. The identification of single nucleotide...

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Veröffentlicht in:	Current neuropharmacology 2017-01, Vol.15 (6), p.831-860
Hauptverfasser:	Naß, Janine, Efferth, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic receptors Butyric acid Catechol Catechol O-methyltransferase Clinical trials Dopamine Dopamine D2 receptors Dopamine β-monooxygenase Drug development Drug therapy Glucocorticoids Glutamic acid receptors Hydrolase Hydroxylase Kinases Methyltransferase Military personnel N-Methyl-D-aspartic acid receptors Neurotransmitters Pharmacogenetics Post traumatic stress disorder Serotonin uptake inhibitors Single-nucleotide polymorphism Tropomyosin
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