No increase in free fetal DNA level in ectopic pregnancy: A preliminary study
The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry. Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective...
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Veröffentlicht in: | Journal of Turkish Society of Obstetric and Gynecology 2017-09, Vol.14 (3), p.156-159 |
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container_title | Journal of Turkish Society of Obstetric and Gynecology |
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creator | Kömürcü Karuserci, Özge Uğur, Mete Gürol Balat, Özcan Sucu, Seyhun |
description | The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry.
Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry.
There were no differences between the two groups in terms of cffDNA absorbance levels.
Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated. |
doi_str_mv | 10.4274/tjod.54715 |
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Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry.
There were no differences between the two groups in terms of cffDNA absorbance levels.
Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated.</description><identifier>ISSN: 2149-9322</identifier><identifier>ISSN: 1307-699X</identifier><identifier>EISSN: 2149-9330</identifier><identifier>DOI: 10.4274/tjod.54715</identifier><identifier>PMID: 29085704</identifier><language>eng</language><publisher>Turkey: Türk Jinekoloji ve Obstetrik Derneği</publisher><subject>Clinical Investigation ; Kadın Hastalıkları ; Tıp</subject><ispartof>Journal of Turkish Society of Obstetric and Gynecology, 2017-09, Vol.14 (3), p.156-159</ispartof><rights>Copyright 2017 by Turkish Society of Obstetrics and Gynecology Turkish Journal of Obstetrics and Gynecology published by Galenos Publishing House. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651889/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651889/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29085704$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Çalışkan,Eray</contributor><creatorcontrib>Kömürcü Karuserci, Özge</creatorcontrib><creatorcontrib>Uğur, Mete Gürol</creatorcontrib><creatorcontrib>Balat, Özcan</creatorcontrib><creatorcontrib>Sucu, Seyhun</creatorcontrib><title>No increase in free fetal DNA level in ectopic pregnancy: A preliminary study</title><title>Journal of Turkish Society of Obstetric and Gynecology</title><addtitle>Turk J Obstet Gynecol</addtitle><description>The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry.
Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry.
There were no differences between the two groups in terms of cffDNA absorbance levels.
Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated.</description><subject>Clinical Investigation</subject><subject>Kadın Hastalıkları</subject><subject>Tıp</subject><issn>2149-9322</issn><issn>1307-699X</issn><issn>2149-9330</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpVkUtLAzEUhYMoKtWNP0BmpwjVPCZN4kIovqHWja5DJnNHU9KkJjNC_71Tq0VX9_VxOJeD0BHB5yUV5UU7i_U5LwXhW2ifklINFWN4e9NTuocOc55hjIkUQhG6i_aowpILXO6jp2ksXLAJTIa-KZoEUDTQGl_cTMeFh0_wqz3YNi6cLRYJ3oIJdnlZjFeDd3MXTFoWue3q5QHaaYzPcPhTB-j17vbl-mE4eb5_vB5PhpYx1g4Ft3w0qixu6qoyfGRF1ZSsIqauK1wxCoA5AaNILZkyliiBG9vIHhfSMFqyAbpa6y66ag61hdAm4_UiuXnvRUfj9P9LcO_6LX5qPuJEStULnP4IpPjRQW713GUL3psAscuaKC45k6WiPXqyRl0NxsfgXQA9i10K_Yf68eZ2PNFcEox78mxN2hRzTtBsDBGsV2HpVVj6O6wePv77wgb9jYZ9Af3PkM4</recordid><startdate>20170901</startdate><enddate>20170901</enddate><creator>Kömürcü Karuserci, Özge</creator><creator>Uğur, Mete Gürol</creator><creator>Balat, Özcan</creator><creator>Sucu, Seyhun</creator><general>Türk Jinekoloji ve Obstetrik Derneği</general><general>Galenos Publishing</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IEBAR</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170901</creationdate><title>No increase in free fetal DNA level in ectopic pregnancy: A preliminary study</title><author>Kömürcü Karuserci, Özge ; Uğur, Mete Gürol ; Balat, Özcan ; Sucu, Seyhun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c333t-75c566bc0fdbba56c7bf43b1addb0b32ee051ea91d839ac1970fcf80fd78a3243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Clinical Investigation</topic><topic>Kadın Hastalıkları</topic><topic>Tıp</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kömürcü Karuserci, Özge</creatorcontrib><creatorcontrib>Uğur, Mete Gürol</creatorcontrib><creatorcontrib>Balat, Özcan</creatorcontrib><creatorcontrib>Sucu, Seyhun</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Idealonline online kütüphane - Journals</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Turkish Society of Obstetric and Gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kömürcü Karuserci, Özge</au><au>Uğur, Mete Gürol</au><au>Balat, Özcan</au><au>Sucu, Seyhun</au><au>Çalışkan,Eray</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>No increase in free fetal DNA level in ectopic pregnancy: A preliminary study</atitle><jtitle>Journal of Turkish Society of Obstetric and Gynecology</jtitle><addtitle>Turk J Obstet Gynecol</addtitle><date>2017-09-01</date><risdate>2017</risdate><volume>14</volume><issue>3</issue><spage>156</spage><epage>159</epage><pages>156-159</pages><issn>2149-9322</issn><issn>1307-699X</issn><eissn>2149-9330</eissn><abstract>The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry.
Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry.
There were no differences between the two groups in terms of cffDNA absorbance levels.
Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated.</abstract><cop>Turkey</cop><pub>Türk Jinekoloji ve Obstetrik Derneği</pub><pmid>29085704</pmid><doi>10.4274/tjod.54715</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5651889 |
source | PubMed Central; Alma/SFX Local Collection |
subjects | Clinical Investigation Kadın Hastalıkları Tıp |
title | No increase in free fetal DNA level in ectopic pregnancy: A preliminary study |
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