VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction

Eukaryotic cells use conserved multisubunit membrane tethering complexes, including CORVET (class C core vacuole/endosome tethering) and HOPS (homotypic fusion and vacuole protein sorting), to control the fusion of endomembranes. These complexes have been extensively studied in yeast, but to date th...

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Veröffentlicht in:Biochemical journal 2017-11, Vol.474 (21), p.3615-3626
Hauptverfasser: Hunter, Morag R, Scourfield, Edward J, Emmott, Edward, Graham, Stephen C
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Sprache:eng
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