Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy

The availability of tyrosine kinase inhibitors (TKI) during the past ten years has led to improved response and overall survival of patients suffering from metastatic clear cell renal cell carcinoma (ccRCC). However, most of these tumors will eventually progress due to resistance evolving under ther...

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Veröffentlicht in:Oncotarget 2017-09, Vol.8 (43), p.74049-74057
Hauptverfasser: Dietz, Steffen, Sültmann, Holger, Du, YueJun, Reisinger, Eva, Riediger, Anja Lisa, Volckmar, Anna-Lena, Stenzinger, Albrecht, Schlesner, Matthias, Jäger, Dirk, Hohenfellner, Markus, Duensing, Stefan, Grüllich, Carsten, Pahernik, Sascha
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Sprache:eng
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